December 12, 2018
The riddle of orange hair was much more complex than previously thought.
They thought the children would be born JING I was Two copies of a gene called MC1R, one from the mother and one from the father, need to be inherited.
God MC1R It The Recessive Garden, That is, it is Can not be expressed in the presence of a dominant gene And only when the person receives the maternal and paternal copies.
Yet, Not all people who inherited the MC1R gene have orange hair, The reason why scientists suspected that other factors played an important role that they do not know until now.
Research of University of Edinburgh, UK Just proved why the gene MC1R This only explains part of the riddle. This is the largest genetic study done on jing so far.
About 1 to 2% of the world's population is jing, but In Scotland, nearly 13%, Which is equivalent to 650 thousand people, according to the project Scotland.
The scientists of University of Edinburgh They examined the DNA of almost 350,000 people who participated in the British project called Great Britain, Which collects information on the genome health of more than 400 thousand people UK
When researchers compared the genome of jing to that of people with brown or black hair, they found Eight differences related to hair color. And they also found it Some genes control when MC1R is pronounced or not.
The orange hair Is not only the result of a recessive gene, But of A complex interaction of at least eight genes.
In addition, researchers have been verified Differences in almost 200 genes associated with people with blond or dark hair.
there is Color The color of the color is black, dark brown, light brown and blond. And that gradient, is Caused by an increasing number of variants in those 200 genes.
Something that surprised the scientists is that many of them These genetic differences are not related to pigmentation, But to the hair texture. Other variants determine how the hair grows, that is, whether it is straight or curly.
"Our work breaks down most of the genetic variations that contribute to hair color differences"Please specify Albert Tansa, One of the researchers The Rosslin Institute of University of Edinburgh.
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