Wednesday, December 12,
God The Argentine Company of Biophysics (SAB) Received the Jorge Pons Hornos Award on Tucumana Florencia González Lizárraga, Which competed against 350 works of the area displayed from different parts of the country. The second reference was to another Tucuman, Luca Medina.
The study presented by Gonzalez Lizraga, "COL-3 inhibits the pathogenesis of alpha-synuclein and reshapes the maturation of amyloid fibers: a possible compound for neuroproductive reuse" Was carried out at the Institute of Applied Molecular and Applied Medicine (IMMCA) of triple dependence between the National University of Tucuman, CONICET and the Ministry of Health of Tucuman, under Rosanna, China.
According to the Secretariat of Science, Art and Technological Innovation, the work also collaborated with the Center for Advanced Microscopy (CMA) of the University of Buenos Aires under the direction of Lea Pietersanta.
González Lizarraga noted that COL-3 is a substance derived from tetracycline, which is chemically modified so that its antibiotic activity has diminished. The advantage is that it is not antibiotics, it can be used for prolonged treatments such as neurodegenerative diseases, thus preventing the generation of resistance bacteria.
The young researcher said that Cole-3 would be better than doxycycline in terms of its neurophrotective effect. This antibiotic has been studied by Tucumán researchers over the past few years for its neurophotogenic effects. The researchers found that it has anti-inflammatory and antigrugent properties that lead to the formation of non-toxic species of alpha-synuclein and a benefit of doxycycline, and that it has the ability to separate the separate fibers and are toxic in Parkinson's disease.
On the other hand, the SAB received the second award of the Hornos Ponce Award to Tucumana Luce,. It was his A study of the interaction of doxycycline in tau protein, and created less toxic species in Alzheimer's patients. Aggregation of this protein is considered to be the main cause of neuronal death in this disease.
Three other researchers from Tucuman took part in the conference: Banjomin, Susias, Natalia Rios Colombo and Fernando Dupuy. In addition, the SAB Board of Directors was registered with Cesar Avila as a member.
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