A team around Dr. Derek Chan of McMaster University in Ontario, Canada, Now analyze the existing literature to determine the benefits and dangers of OIT in peanut allergy. A total of 12 clinical trials from different continents with a total of 1041 subjects and an average observation time of 1 year included the meta-analysis. So far, the success of OIT in clinical trials with a relatively small number of participants is judged by whether subjects after intervention under controlled conditions in the clinic undergo an oral provocation test, so tolerate certain amounts of protein. And they do, as the meta-analysis shows. The chance of passing the provocation test was 12.4 times higher than after OIT than with untreated allergic people.